Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

Glioblastoma multiforme (GBM) is the most aggressive and deadly form of adult brain cancer. Despite of many attempts to identify potential therapies for this disease, including promising cancer immunotherapy approaches, it remains incurable. To address the need of improved persistence, expansion, an...

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Publicado en:PLoS One
Autores principales: Sahin, Ayguen, Sanchez, Carlos, Bullain, Szofia, Waterman, Peter, Weissleder, Ralph, Carter, Bob S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033533/
https://ncbi.nlm.nih.gov/pubmed/29975720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199414
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