Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

Glioblastoma multiforme (GBM) is the most aggressive and deadly form of adult brain cancer. Despite of many attempts to identify potential therapies for this disease, including promising cancer immunotherapy approaches, it remains incurable. To address the need of improved persistence, expansion, an...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Sahin, Ayguen, Sanchez, Carlos, Bullain, Szofia, Waterman, Peter, Weissleder, Ralph, Carter, Bob S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033533/
https://ncbi.nlm.nih.gov/pubmed/29975720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199414
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