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Selective amplification of polymorphic dihydrofolate reductase gene loci in Chinese hamster lung cells.

A series of antifolate-resistant Chinese hamster lung sublines that overproduce either a Mr 20,000 or a Mr 21,000 class of dihydrofolate reductase (DHFR; tetrahydrofolate dehydrogenase; 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase, EC 1.5.1.3), known to contain amplified DHFR genes, has been analyz...

詳細記述

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書誌詳細
主要な著者: Lewis, J A, Davide, J P, Melera, P W
フォーマット: Artigo
言語:Inglês
出版事項: 1982
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC347254/
https://ncbi.nlm.nih.gov/pubmed/6184719
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