SYNTHESIS AND BIOLOGICAL EVALUATION OF BIARYL ANALOGS OF ANTITUBULIN COMPOUNDS

This paper reports the synthesis of methanones and esters bearing different substitution patterns as spacer groups between aromatic rings. This series of compounds can be considered phenstatin analogs. Two of the newly synthesized compounds, 5a and 5c, strongly inhibited tubulin polymerization and t...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tozatti, Camila Santos Suniga, Khodyuk, Rejane Gonçalves Diniz, da Silva, Adriano Olimpio, dos Santos, Edson dos Anjos, de Lima, Marcos Serrou do Amaral e Dênis Pires, Hamel, Ernest
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472429/
https://ncbi.nlm.nih.gov/pubmed/23087491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S0100-40422012000900010
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky