Phase II Trial of Intravenous Administration of Reolysin(®) (Reovirus Serotype-3-dearing Strain) in Patients with Metastatic Melanoma

Reovirus, a replication competent RNA virus, has preclinical activity against melanoma lines and xenografts. We conducted a phase II trial of reovirus in metastatic melanoma patients. Patients received 3 × 10(10) TCID50 on days 1–5 of each 28 day cycle, administered intravenously. Twenty-one eligibl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Galanis, Evanthia, Markovic, Svetomir N, Suman, Vera J, Nuovo, Gerard J, Vile, Richard G, Kottke, Timothy J, Nevala, Wendy K, Thompson, Michael A, Lewis, Jean E, Rumilla, Kandelaria M, Roulstone, Victoria, Harrington, Kevin, Linette, Gerald P, Maples, William J, Coffey, Matt, Zwiebel, James, Kendra, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464629/
https://ncbi.nlm.nih.gov/pubmed/22871663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.146
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados