Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy

Oncolytic reovirus is currently under active investigation in a range of tumour types. Early phase studies have shown that this agent has modest monotherapy efficacy and its future development is likely to focus on combination regimens with cytotoxic chemotherapy. Indeed, phase I/II clinical trials...

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Publicat a:Gene Ther
Autors principals: Roulstone, V, Twigger, K, Zaidi, S, Pencavel, T, Kyula, JN, White, C, McLaughlin, M, Seth, R, Karapanagiotou, EM, Mansfield, D, Coffey, M, Nuovo, G, Vile, RG, Pandha, HS, Melcher, AA, Harrington, KJ
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821071/
https://ncbi.nlm.nih.gov/pubmed/22895509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.68
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