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Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity

Reovirus is a naturally occurring oncolytic virus currently in early clinical trials. However, the rapid induction of neutralizing antibodies represents a major obstacle to successful systemic delivery. This study addresses, for the first time, the ability of cellular carriers in the form of T cells...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Gene Ther
Κύριοι συγγραφείς: Ilett, EJ, Prestwich, RJ, Kottke, T, Errington, F, Thompson, JM, Harrington, KJ, Pandha, HS, Coffey, M, Selby, PJ, Vile, RG, Melcher, AA
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562026/
https://ncbi.nlm.nih.gov/pubmed/19282847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.29
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