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Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma

Reovirus is a promising unmodified double-stranded RNA (dsRNA) anti-cancer oncolytic virus, which is thought to specifically target cells with activated Ras. Although reovirus has been tested in a wide range of preclinical models and has entered early clinical trials, it has not previously been test...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Errington, F, White, CL, Twigger, KR, Rose, A, Scott, K, Steele, L, Ilett, LJ, Prestwich, R, Pandha, HS, Coffey, M, Selby, P, Vile, R, Harrington, KJ, Melcher, AA
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821075/
https://ncbi.nlm.nih.gov/pubmed/18401435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2008.58
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