Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy

Oncolytic reovirus is currently under active investigation in a range of tumour types. Early phase studies have shown that this agent has modest monotherapy efficacy and its future development is likely to focus on combination regimens with cytotoxic chemotherapy. Indeed, phase I/II clinical trials...

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Gepubliceerd in:Gene Ther
Hoofdauteurs: Roulstone, V, Twigger, K, Zaidi, S, Pencavel, T, Kyula, JN, White, C, McLaughlin, M, Seth, R, Karapanagiotou, EM, Mansfield, D, Coffey, M, Nuovo, G, Vile, RG, Pandha, HS, Melcher, AA, Harrington, KJ
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821071/
https://ncbi.nlm.nih.gov/pubmed/22895509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.68
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