Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

Multiple studies have indicated that the TET oxidases and, more controversially, the activation-induced cytidine deaminase/APOBEC deaminases have the capacity to convert genomic DNA 5-methylcytosine (MeC) into altered nucleobases that provoke excision repair and culminate in the replacement of the o...

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Hlavní autoři: Carpenter, Michael A., Li, Ming, Rathore, Anurag, Lackey, Lela, Law, Emily K., Land, Allison M., Leonard, Brandon, Shandilya, Shivender M. D., Bohn, Markus-Frederik, Schiffer, Celia A., Brown, William L., Harris, Reuben S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464582/
https://ncbi.nlm.nih.gov/pubmed/22896697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385161
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