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DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B
APOBEC (apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like) is a family of enzymes that deaminates cytosine (C) to uracil (U) on nucleic acid. APOBEC3B (A3B) functions in innate immunity against intrinsic and invading retroelements and viruses. A3B can also induce genomic DNA mutations...
में बचाया:
में प्रकाशित: | Biochem J |
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मुख्य लेखकों: | , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Portland Press Ltd.
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613526/ https://ncbi.nlm.nih.gov/pubmed/26195824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150382 |
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