DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B

APOBEC (apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like) is a family of enzymes that deaminates cytosine (C) to uracil (U) on nucleic acid. APOBEC3B (A3B) functions in innate immunity against intrinsic and invading retroelements and viruses. A3B can also induce genomic DNA mutations...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem J
Egile Nagusiak: Fu, Yang, Ito, Fumiaki, Zhang, Gewen, Fernandez, Braulio, Yang, Hanjing, Chen, Xiaojiang S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2015
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613526/
https://ncbi.nlm.nih.gov/pubmed/26195824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150382
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