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Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination

Humans have seven APOBEC3 DNA cytosine deaminases. The activity of these enzymes allows them to restrict a variety of retroviruses and retrotransposons, but may also cause pro-mutagenic genomic uracil lesions. During interphase the APOBEC3 proteins have different subcellular localizations: cell-wide...

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Bibliografski detalji
Glavni autori: Lackey, Lela, Law, Emily K., Brown, William L., Harris, Reuben S.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610724/
https://ncbi.nlm.nih.gov/pubmed/23388464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23713
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