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Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination
Humans have seven APOBEC3 DNA cytosine deaminases. The activity of these enzymes allows them to restrict a variety of retroviruses and retrotransposons, but may also cause pro-mutagenic genomic uracil lesions. During interphase the APOBEC3 proteins have different subcellular localizations: cell-wide...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610724/ https://ncbi.nlm.nih.gov/pubmed/23388464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23713 |
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