Conformational Flexibility Determines Selectivity and Antibacterial, Antiplasmodial, and Anticancer Potency of Cationic α-Helical Peptides

We used a combination of fluorescence, circular dichroism (CD), and NMR spectroscopies in conjunction with size exclusion chromatography to help rationalize the relative antibacterial, antiplasmodial, and cytotoxic activities of a series of proline-free and proline-containing model antimicrobial pep...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vermeer, Louic S., Lan, Yun, Abbate, Vincenzo, Ruh, Emrah, Bui, Tam T., Wilkinson, Louise J., Kanno, Tokuwa, Jumagulova, Elmira, Kozlowska, Justyna, Patel, Jayneil, McIntyre, Caitlin A., Yam, W. C., Siu, Gilman, Atkinson, R. Andrew, Lam, Jenny K. W., Bansal, Sukhvinder S., Drake, Alex F., Mitchell, Graham H., Mason, A. James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Membrane Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464521/
https://ncbi.nlm.nih.gov/pubmed/22869378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359067
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