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Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer
Cationic amphipathic histidine rich peptides demonstrate differential nucleic acid binding capabilities at neutral and acidic pH and adopt conformations at acidic pH that enable interaction with endosomal membranes, their subsequent disordering and facilitate entry of cargo to the cell cytosol. To b...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378503/ https://ncbi.nlm.nih.gov/pubmed/22226847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2011.12.018 |
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