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Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice

RATIONALE: Alleviating addiction to tobacco products could prevent millions of deaths. Investigating novel compounds selectively targeting α4β2 nAChRs hypothesized to have a key role in the rewarding effects of nicotine may be a useful approach for future treatment. OBJECTIVES: The present study was...

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Detalhes bibliográficos
Main Authors: Tobey, K. M., Walentiny, D. M., Wiley, J. L., Carroll, F. I., Damaj, M. I., Azar, M. R., Koob, G. F., George, O., Harris, L. S., Vann, R. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464481/
https://ncbi.nlm.nih.gov/pubmed/22526534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2703-3
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