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Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain

Nicotinic acetylcholine receptors containing α4 subunits (α4β2* nAChRs) are critical for nicotinic cholinergic transmission and the addictive action of nicotine. To identify specific activities of these receptors in the adult mouse brain, we coupled targeted deletion of α4 nAChR subunits with behavi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Peng, Can, Engle, Staci E., Yan, Yijin, Weera, Marcus M., Berry, Jennifer N., Arvin, Matthew C., Zhao, Guiqing, McIntosh, J. Michael, Chester, Julia A., Drenan, Ryan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536316/
https://ncbi.nlm.nih.gov/pubmed/28759616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182142
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