Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward

Upregulation of β2 subunit-containing (β2*) nicotinic acetylcholine receptors (nAChRs) is implicated in several aspects of nicotine addiction, and menthol cigarette smokers tend to upregulate β2* nAChRs more than nonmenthol cigarette smokers. We investigated the effect of long-term menthol alone on...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Henderson, Brandon J., Wall, Teagan R., Henley, Beverley M., Kim, Charlene H., Nichols, Weston A., Moaddel, Ruin, Xiao, Cheng, Lester, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783498/
https://ncbi.nlm.nih.gov/pubmed/26961950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4194-15.2016
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