Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing

Menthol contributes to poor cessation rates among smokers, in part because menthol enhances nicotine reward and reinforcement. Mentholated tobacco products contain (−)-menthol and (+)-menthol, in varying proportions. We examined these two menthol stereoisomers for their ability to upregulate α4β2 nA...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Henderson, Brandon J., Grant, Stephen, Chu, Betty W., Shahoei, Rezvan, Huard, Stephanie M., Saladi, Shyam S. M., Tajkhorshid, Emad, Dougherty, Dennis A., Lester, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325563/
https://ncbi.nlm.nih.gov/pubmed/30627659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0465-18.2018
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