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Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)(3)(β2)(2) nAChR-Selective Positive Allosteric Modulator

Positive allosteric modulators (PAMs) of nicotinic acetylcholine (ACh) receptors (nAChRs) have potential clinical applications in the treatment of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity, and 3-(2-chlorophenyl)-5-(5-methyl-1-(pipe...

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Publicat a:Mol Pharmacol
Autors principals: Hamouda, Ayman K., Deba, Farah, Wang, Ze-Jun, Cohen, Jonathan B.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851301/
https://ncbi.nlm.nih.gov/pubmed/26976945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103341
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