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Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)(3)(β2)(2) nAChR-Selective Positive Allosteric Modulator

Positive allosteric modulators (PAMs) of nicotinic acetylcholine (ACh) receptors (nAChRs) have potential clinical applications in the treatment of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity, and 3-(2-chlorophenyl)-5-(5-methyl-1-(pipe...

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Bibliografske podrobnosti
izdano v:Mol Pharmacol
Main Authors: Hamouda, Ayman K., Deba, Farah, Wang, Ze-Jun, Cohen, Jonathan B.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851301/
https://ncbi.nlm.nih.gov/pubmed/26976945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103341
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