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Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)(3)(β2)(2) nAChR-Selective Positive Allosteric Modulator

Positive allosteric modulators (PAMs) of nicotinic acetylcholine (ACh) receptors (nAChRs) have potential clinical applications in the treatment of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity, and 3-(2-chlorophenyl)-5-(5-methyl-1-(pipe...

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Publicado en:Mol Pharmacol
Main Authors: Hamouda, Ayman K., Deba, Farah, Wang, Ze-Jun, Cohen, Jonathan B.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851301/
https://ncbi.nlm.nih.gov/pubmed/26976945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103341
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