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Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)(3)(β2)(2) nAChR-Selective Positive Allosteric Modulator

Positive allosteric modulators (PAMs) of nicotinic acetylcholine (ACh) receptors (nAChRs) have potential clinical applications in the treatment of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity, and 3-(2-chlorophenyl)-5-(5-methyl-1-(pipe...

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Bibliografiske detaljer
Udgivet i:Mol Pharmacol
Main Authors: Hamouda, Ayman K., Deba, Farah, Wang, Ze-Jun, Cohen, Jonathan B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851301/
https://ncbi.nlm.nih.gov/pubmed/26976945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.103341
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