Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses

Neuronal nicotinic acetylcholine receptors (nAChRs) are promising drug targets to manage several neurological disorders and nicotine addiction. Growing evidence indicates that positive allosteric modulators of nAChRs improve pharmacological specificity by binding to unique sites present only in a su...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Wang, Ze-Jun, Deba, Farah, Mohamed, Tasnim S., Chiara, David C., Ramos, Kara, Hamouda, Ayman K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473250/
https://ncbi.nlm.nih.gov/pubmed/28446611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771246
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares