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Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
Intracerebral injection of brain extracts containing amyloid or tau aggregates in transgenic animals can induce cerebral amyloidosis and tau pathology. We extracted pure populations of tau oligomers directly from the cerebral cortex of Alzheimer disease (AD) brain. These oligomers are potent inhibit...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463004/ https://ncbi.nlm.nih.gov/pubmed/23050084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00700 |
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