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Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

Intracerebral injection of brain extracts containing amyloid or tau aggregates in transgenic animals can induce cerebral amyloidosis and tau pathology. We extracted pure populations of tau oligomers directly from the cerebral cortex of Alzheimer disease (AD) brain. These oligomers are potent inhibit...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lasagna-Reeves, Cristian A., Castillo-Carranza, Diana L., Sengupta, Urmi, Guerrero-Munoz, Marcos J., Kiritoshi, Takaki, Neugebauer, Volker, Jackson, George R., Kayed, Rakez
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463004/
https://ncbi.nlm.nih.gov/pubmed/23050084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00700
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