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A New Approach for Pyrazinamide Susceptibility Testing in Mycobacterium tuberculosis
Background: Pyrazinamide (PZA) is an important drug in the treatment of tuberculosis. Microbiological methods of PZA susceptibility testing are controversial and have low reproducibility. After conversion of PZA into pyrazinoic acid (POA) by the bacterial pyrazinamidase enzyme, the drug is expelled...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Mary Ann Liebert, Inc.
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462410/ https://ncbi.nlm.nih.gov/pubmed/22372927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mdr.2011.0207 |
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