EFFECT OF PYRAZINAMIDASE ACTIVITY ON PYRAZINAMIDE RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS

Resistance of Mycobacterium tuberculosis to pyrazinamide is associated with mutations in the pncA gene, which codes for pyrazinamidase. The association between the enzymatic activity of mutated pyrazinamidases and the level of pyrazinamide resistance remains poorly understood. Twelve M. tuberculosis...

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Detaylı Bibliyografya
Asıl Yazarlar: Sheen, Patricia, Ferrer, Patricia, Gilman, Robert H., López-Llano, Jon, Fuentes, Patricia, Valencia, Eddy, Zimic, Mirko J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691962/
https://ncbi.nlm.nih.gov/pubmed/19249243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2009.01.004
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