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EFFECT OF PYRAZINAMIDASE ACTIVITY ON PYRAZINAMIDE RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS

Resistance of Mycobacterium tuberculosis to pyrazinamide is associated with mutations in the pncA gene, which codes for pyrazinamidase. The association between the enzymatic activity of mutated pyrazinamidases and the level of pyrazinamide resistance remains poorly understood. Twelve M. tuberculosis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sheen, Patricia, Ferrer, Patricia, Gilman, Robert H., López-Llano, Jon, Fuentes, Patricia, Valencia, Eddy, Zimic, Mirko J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691962/
https://ncbi.nlm.nih.gov/pubmed/19249243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2009.01.004
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