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EFFECT OF PYRAZINAMIDASE ACTIVITY ON PYRAZINAMIDE RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS

Resistance of Mycobacterium tuberculosis to pyrazinamide is associated with mutations in the pncA gene, which codes for pyrazinamidase. The association between the enzymatic activity of mutated pyrazinamidases and the level of pyrazinamide resistance remains poorly understood. Twelve M. tuberculosis...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sheen, Patricia, Ferrer, Patricia, Gilman, Robert H., López-Llano, Jon, Fuentes, Patricia, Valencia, Eddy, Zimic, Mirko J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691962/
https://ncbi.nlm.nih.gov/pubmed/19249243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2009.01.004
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