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pncA gene expression and prediction factors on pyrazinamide resistance in Mycobacterium tuberculosis
BACKGROUND: Mutations in the pyrazinamidase (PZAse) coding gene, pncA, have been considered as the main cause of pyrazinamide (PZA) resistance in Mycobacterium tuberculosis. However, recent studies suggest there is no single mechanism of resistance to PZA. The pyrazinoic acid (POA) efflux rate is th...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3755357/ https://ncbi.nlm.nih.gov/pubmed/23867321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2013.03.005 |
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