Structure-Activity relationship in mutated pyrazinamidases from Mycobacterium tuberculosis

The pncA gene codes the pyrazinamidase of Mycobacterium tuberculosis, which converts pyrazinamide to ammonia and pyrazinoic-acid, the active antituberculous compound. Pyrazinamidase mutations are associated to pyrazinamide-resistant phenotype, however how mutations affect the structure of the pyrazi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Quiliano, Miguel, Gutierrez, Andres Hazaet, Gilman, Robert Hugh, López, César, Evangelista, Wilfredo, Sotelo, Jun, Sheen, Patricia, Zimic, Mirko
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Biomedical Informatics 2011
विषय:
Hypothesis
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143395/
https://ncbi.nlm.nih.gov/pubmed/21814390
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन