MODS-Wayne, a Colorimetric Adaptation of the Microscopic-Observation Drug Susceptibility (MODS) Assay for Detection of Mycobacterium tuberculosis Pyrazinamide Resistance from Sputum Samples

Although pyrazinamide (PZA) is a key component of first- and second-line tuberculosis treatment regimens, there is no gold standard to determine PZA resistance. Approximately 50% of multidrug-resistant tuberculosis (MDR-TB) and over 90% of extensively drug-resistant tuberculosis (XDR-TB) strains are...

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Dettagli Bibliografici
Pubblicato in:J Clin Microbiol
Autori principali: Alcántara, Roberto, Fuentes, Patricia, Antiparra, Ricardo, Santos, Marco, Gilman, Robert H., Kirwan, Daniela E., Zimic, Mirko, Sheen, Patricia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Mycobacteriology and Aerobic Actinomycetes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355525/
https://ncbi.nlm.nih.gov/pubmed/30429257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01162-18
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