Sputum PCR-Single-Strand Conformational Polymorphism Test for Same-Day Detection of Pyrazinamide Resistance in Tuberculosis Patients

Pyrazinamide is a first-line drug for treating tuberculosis, but pyrazinamide resistance testing is usually too slow to guide initial therapy, so some patients receive inappropriate therapy. We therefore aimed to optimize and evaluate a rapid molecular test for tuberculosis drug resistance to pyrazi...

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Hlavní autoři: Sheen, Patricia, Méndez, Melissa, Gilman, Robert H., Peña, Lizeth, Caviedes, Luz, Zimic, Mirko J., Zhang, Ying, Moore, David A. J., Evans, Carlton A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Mycobacteriology and Aerobic Actinomycetes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738130/
https://ncbi.nlm.nih.gov/pubmed/19535526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01594-08
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