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IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice
Alcoholic liver disease (ALD) is characterized by steatosis and upregulation of proinflammatory cytokines, including IL-1β. IL-1β, type I IL-1 receptor (IL-1R1), and IL-1 receptor antagonist (IL-1Ra) are all important regulators of the IL-1 signaling complex, which plays a role in inflammation. Furt...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461900/ https://ncbi.nlm.nih.gov/pubmed/22945633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60777 |
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