MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis

BACKGROUND & AIM: MicroRNAs (miRs) regulate hepatic steatosis, inflammation and fibrosis. Fibrosis is the consequence of chronic tissue damage and inflammation. We hypothesized that deficiency of miR-155, a master regulator of inflammation, attenuates steatohepatitis and fibrosis. METHODS: Wild...

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Vydáno v:PLoS One
Hlavní autoři: Csak, Timea, Bala, Shashi, Lippai, Dora, Kodys, Karen, Catalano, Donna, Iracheta-Vellve, Arvin, Szabo, Gyongyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456142/
https://ncbi.nlm.nih.gov/pubmed/26042593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129251
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