Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice

Mitochondrial dysfunction is a pathogenic feature of non-alcoholic steatohepatitis (NASH). NASH complicates hepatotropic viral disease. The mitochondrial antiviral signaling protein, (MAVS) is the adapter of helicase receptors involved in sensing dsRNA. We hypothesized that impaired MAVS function ma...

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Bibliografiske detaljer
Main Authors: Csak, Timea, Dolganiuc, Angela, Kodys, Karen, Nath, Bharath, Petrasek, Jan, Bala, Shashi, Lippai, Dora, Szabo, Gyongyi
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253554/
https://ncbi.nlm.nih.gov/pubmed/21425308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24301
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