Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice

Mitochondrial dysfunction is a pathogenic feature of non-alcoholic steatohepatitis (NASH). NASH complicates hepatotropic viral disease. The mitochondrial antiviral signaling protein, (MAVS) is the adapter of helicase receptors involved in sensing dsRNA. We hypothesized that impaired MAVS function ma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Csak, Timea, Dolganiuc, Angela, Kodys, Karen, Nath, Bharath, Petrasek, Jan, Bala, Shashi, Lippai, Dora, Szabo, Gyongyi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253554/
https://ncbi.nlm.nih.gov/pubmed/21425308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24301
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