Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice

Mitochondrial dysfunction is a pathogenic feature of non-alcoholic steatohepatitis (NASH). NASH complicates hepatotropic viral disease. The mitochondrial antiviral signaling protein, (MAVS) is the adapter of helicase receptors involved in sensing dsRNA. We hypothesized that impaired MAVS function ma...

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Main Authors: Csak, Timea, Dolganiuc, Angela, Kodys, Karen, Nath, Bharath, Petrasek, Jan, Bala, Shashi, Lippai, Dora, Szabo, Gyongyi
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253554/
https://ncbi.nlm.nih.gov/pubmed/21425308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24301
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