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Endoplasmic Reticulum Stress Is Important for the Manifestations of α-Synucleinopathy In Vivo
Accumulation of misfolded α-synuclein (αS) is mechanistically linked to neurodegeneration in Parkinson's disease (PD) and other α-synucleinopathies. However, how αS causes neurodegeneration is unresolved. Because cellular accumulation of misfolded proteins can lead to endoplasmic reticulum stre...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461828/ https://ncbi.nlm.nih.gov/pubmed/22399753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5367-11.2012 |
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