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Hepatic and Extrahepatic Sources and Manifestations in Endoplasmic Reticulum Storage Diseases
Alpha-1-antitrypsin (AAT) and fibrinogen are secretory acute phase reactant proteins. Circulating AAT and fibrinogen are synthesized exclusively in the liver. Mutations in the encoding genes result in conformational abnormalities of the two molecules that aggregate within the rough endoplasmic retic...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8198767/ https://ncbi.nlm.nih.gov/pubmed/34071368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115778 |
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