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Fibrinogen Brescia : Hepatic Endoplasmic Reticulum Storage and Hypofibrinogenemia Because of a γ284 Gly→Arg Mutation

The proposita suffered from liver cirrhosis and biopsy showed type 1 membrane-bound fiberglass inclusions. The hepatic inclusion bodies were weakly periodic acid-Schiff diastase-positive, and on immunoperoxidase staining reacted specifically with anti-fibrinogen antisera. Coagulation investigations...

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Detalhes bibliográficos
Main Authors: Brennan, Stephen O., Wyatt, Jane, Medicina, Daniela, Callea, Francesco, George, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850222/
https://ncbi.nlm.nih.gov/pubmed/10880389
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