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Corruption and Spread of Pathogenic Proteins in Neurodegenerative Diseases
With advancing age, the brain becomes increasingly susceptible to neurodegenerative diseases, most of which are characterized by the misfolding and errant aggregation of certain proteins. The induction of aggregation involves a crystallization-like seeding mechanism by which a specific protein is st...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460416/ https://ncbi.nlm.nih.gov/pubmed/22879600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.399378 |
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