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Corruption and Spread of Pathogenic Proteins in Neurodegenerative Diseases
With advancing age, the brain becomes increasingly susceptible to neurodegenerative diseases, most of which are characterized by the misfolding and errant aggregation of certain proteins. The induction of aggregation involves a crystallization-like seeding mechanism by which a specific protein is st...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460416/ https://ncbi.nlm.nih.gov/pubmed/22879600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.399378 |
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