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Corruption and Spread of Pathogenic Proteins in Neurodegenerative Diseases

With advancing age, the brain becomes increasingly susceptible to neurodegenerative diseases, most of which are characterized by the misfolding and errant aggregation of certain proteins. The induction of aggregation involves a crystallization-like seeding mechanism by which a specific protein is st...

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Bibliografski detalji
Glavni autori: Walker, Lary C., LeVine, Harry
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460416/
https://ncbi.nlm.nih.gov/pubmed/22879600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.399378
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