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What Amyloid Ligands can tell us about Molecular Polymorphism and Disease

Brain-penetrant PET imaging ligands selective for amyloid pathology in living subjects have sparked a revolution in presymptomatic biomarkers for Alzheimer’s disease progression. As additional chemical structures were investigated, the heterogeneity of ligand binding sites became apparent, as did di...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: LeVine, Harry, Walker, Lary C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857207/
https://ncbi.nlm.nih.gov/pubmed/27143437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.03.019
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