Loading...

Fragment Screening at Adenosine-A(3) Receptors in Living Cells Using a Fluorescence-Based Binding Assay

G protein-coupled receptors (GPCRs) comprise the largest family of transmembrane proteins. For GPCR drug discovery, it is important that ligand affinity is determined in the correct cellular environment and preferably using an unmodified receptor. We developed a live cell high-content screening assa...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Stoddart, Leigh A., Vernall, Andrea J., Denman, Jessica L., Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3456874/
https://ncbi.nlm.nih.gov/pubmed/22999879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.07.014
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!