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Nucleic acid-binding molecules with high affinity and base sequence specificity: intercalating agents covalently linked to oligodeoxynucleotides.

Oligodeoxyribonucleotides covalently linked to an intercalating agent via a polymethylene linker were synthesized. Oligothymidylates attached to an acridine dye (Acr) through the 3'-phosphate group [(Tp)n(CH2) mAcr ] specifically interact with the complementary sequence. The interaction is stro...

詳細記述

保存先:
書誌詳細
主要な著者: Asseline, U, Delarue, M, Lancelot, G, Toulmé, F, Thuong, N T, Montenay-Garestier, T, Hélène, C
フォーマット: Artigo
言語:Inglês
出版事項: 1984
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC345494/
https://ncbi.nlm.nih.gov/pubmed/6587350
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