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Lower Than Expected Maraviroc Concentrations in Cerebrospinal Fluid Exceed the Wild-Type CCR5-tropic HIV-1 50% Inhibitory Concentration
OBJECTIVES: to measure maraviroc total cerebrospinal fluid (CSF) concentrations and compare them with total and unbound plasma concentrations. METHODS: Total maraviroc was measured by reverse phase high performance liquid chromatography with tandem mass spectrometry while ultrafiltration was used fo...
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| Hlavní autoři: | , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3454507/ https://ncbi.nlm.nih.gov/pubmed/22313954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328351f627 |
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