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Efavirenz concentrations in CSF exceed IC(50) for wild-type HIV

OBJECTIVES: HIV-associated neurocognitive disorders remain common despite use of potent antiretroviral therapy (ART). Ongoing viral replication due to poor distribution of antivirals into the CNS may increase risk for HIV-associated neurocognitive disorders. This study's objective was to determ...

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Detalhes bibliográficos
Main Authors: Best, Brookie M., Koopmans, Peter P., Letendre, Scott L., Capparelli, Edmund V., Rossi, Steven S., Clifford, David B., Collier, Ann C., Gelman, Benjamin B., Mbeo, Gilbert, McCutchan, J. Allen, Simpson, David M., Haubrich, Richard, Ellis, Ronald, Grant, Igor, Ellis, Ronald J., Marcotte, Thomas D., Franklin, Donald, Alexander, Terry, Letendre, Scott, Capparelli, Edmund, Heaton, Robert K., Atkinson, J. Hampton, Woods, Steven Paul, Dawson, Matthew, Wong, Joseph K., Fennema-Notestine, Christine, Taylor, Michael J., Theilmann, Rebecca, Gamst, Anthony C., Cushman, Clint, Abramson, Ian, Vaida, Florin, von Jaeger, Rodney, McArthur, Justin, Smith, Mary, Morgello, Susan, Simpson, David, Mintz, Letty, Toperoff, Will, Collier, Ann, Marra, Christina, Jones, Trudy, Gelman, Benjamin, Head, Eleanor, Clifford, David, Al-Lozi, Muhammad, Teshome, Mengesha
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019085/
https://ncbi.nlm.nih.gov/pubmed/21098541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq434
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