Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

OBJECTIVE: To evaluate whether penetration of a combination regimen into the central nervous system (CNS), as estimated by the CNS Penetration-Effectiveness (CPE) rank, is associated with lower cerebrospinal fluid (CSF) viral load. DESIGN: Data were analyzed from 467 participants who were human immu...

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Autores principales: Letendre, Scott, Marquie-Beck, Jennifer, Capparelli, Edmund, Best, Brookie, Clifford, David, Collier, Ann C., Gelman, Benjamin B., McArthur, Justin C., McCutchan, J. Allen, Morgello, Susan, Simpson, David, Grant, Igor, Ellis, Ronald J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763187/
https://ncbi.nlm.nih.gov/pubmed/18195140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2007.31
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