LOW CSF Concentrations of the Nucleotide HIV Reverse Transcriptase Inhibitor, Tenofovir

Tenofovir is a nucleotide HIV reverse transcriptase inhibitor whose chemical properties suggest that it may not penetrate into the central nervous system in therapeutic concentrations. The study objective was to determine tenofovir penetration into cerebrospinal fluid (CSF). CHARTER is a multi-cente...

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Detalhes bibliográficos
Main Authors: Best, Brookie M., Letendre, Scott L., Koopmans, Peter, Rossi, Steven S., Clifford, David B., Collier, Ann C., Gelman, Benjamin B., Marra, Christina M., McArthur, Justin C., McCutchan, J. Allen, Morgello, Susan, Simpson, David M., Capparelli, Edmund V., Ellis, Ronald J., Grant, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299895/
https://ncbi.nlm.nih.gov/pubmed/22217676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318247ec54
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