Low atazanavir concentrations in cerebrospinal fluid

OBJECTIVE: Protease inhibitors may not penetrate into the central nervous system in therapeutic concentrations, which may allow ongoing HIV replication and injury. The objective of this study was to determine atazanavir penetration into cerebrospinal fluid (CSF). DESIGN: Single random plasma or pair...

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Detalhes bibliográficos
Main Authors: Best, Brookie M., Letendre, Scott L., Brigid, Eileen, Clifford, David B., Collier, Ann C., Gelman, Benjamin B., McArthur, Justin C., McCutchan, J. Allen, Simpson, David M., Ellis, Ronald, Capparelli, Edmund V., Grant, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642983/
https://ncbi.nlm.nih.gov/pubmed/19050389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328317a702
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