Low atazanavir concentrations in cerebrospinal fluid

OBJECTIVE: Protease inhibitors may not penetrate into the central nervous system in therapeutic concentrations, which may allow ongoing HIV replication and injury. The objective of this study was to determine atazanavir penetration into cerebrospinal fluid (CSF). DESIGN: Single random plasma or pair...

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Autores principales: Best, Brookie M., Letendre, Scott L., Brigid, Eileen, Clifford, David B., Collier, Ann C., Gelman, Benjamin B., McArthur, Justin C., McCutchan, J. Allen, Simpson, David M., Ellis, Ronald, Capparelli, Edmund V., Grant, Igor
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642983/
https://ncbi.nlm.nih.gov/pubmed/19050389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328317a702
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