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Indinavir Population Pharmacokinetics in Plasma and Cerebrospinal Fluid

Plasma and cerebrospinal fluid (CSF) indinavir concentrations were measured by high-performance liquid chromatography. The median concentration in plasma exceeded that in CSF 10-fold. The modeled CSF curve was flat at 155 nM, and the estimated ratio of the areas under the CSF and plasma concentratio...

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Detalhes bibliográficos
Main Authors: Letendre, Scott L., Capparelli, Edmund V., Ellis, Ronald J., McCutchan, J. Allen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90032/
https://ncbi.nlm.nih.gov/pubmed/10898694
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